Prevalence of Methicillin Resistant Staphylococcus aureus and Antibiotic Susceptibility Pattern in a Tertiary Hospital in Nepal

  • Laxmi Kant Khanal Department of Microbiology, Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal
  • Ram Prasad Adhikari Department of Microbiology, Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal
  • Ankita Guragain Department of Microbiology, Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal
DOI: https://doi.org/10.33314/jnhrc.v16i2.1569

Abstract

Background: Methicillin resistant Staphylococcus aureus is a global health challenge nowadays creating problem in antibiotic therapy. This study was aimed to generate resistance pattern of Methicillin resistant Staphylococcus aureus to various antibiotics in order to formulate antibiotic policy for control of Methicillin resistant Staphylococcus aureus in Nepal.
Methods: This was a cross-sectional study conducted at the department of Clinical Microbiology, Nepal Medical College Teaching Hospital, from April 2015 to March 2016. A total of 142 S. aureus isolated from various clinical specimens. were screened for Methicillin resistant Staphylococcus aureus by cefoxitin disc method according to Clinical and Laboratory Standards Institute guidelines.
Results: Out of 142 S. aureus isolates, 30 (21.1%) were detected as Methicillin resistant Staphylococcus aureus by cefoxitin disc method. Most of the Methicillin resistant Staphylococcus aureus (25/30) were isolated from pus which were collected from OPD patients. Antibiotic sensitivity pattern showed all Methicillin resistant Staphylococcus aureus isolates were sensitive to vancomycin.
Conclusions: Prevalence of Methicillin resistant Staphylococcus aureus was found to be 21.1%, and all Methicillin resistant Staphylococcus aureus appear 100% sensitive to vancomycin.
Keywords: Antibiotic Susceptibility Test, MRSA, Nepal, Prevalence.

Published
2018-07-03
How to Cite
KhanalL. K., AdhikariR. P., & GuragainA. (2018). Prevalence of Methicillin Resistant Staphylococcus aureus and Antibiotic Susceptibility Pattern in a Tertiary Hospital in Nepal. Journal of Nepal Health Research Council, 16(2), 172-174. https://doi.org/10.33314/jnhrc.v16i2.1569
Issue
Vol. 16 No. 2 (2018): JNHRC Vol. 16 No. 2 Issue 39 Apr-Jun 2018
Section
Original Article

Copyright (c) 2018 Laxmi Kant Khanal, Ram Prasad Adhikari, Ankita Guragain

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